These four protein complexes are the NADH:ubiquinone oxidoreductase complex (complex I of the respiratory chain), the succinate dehydrogenase complex (complex II of the respiratory chain), CDP-diacylglycerolinositol 3-phosphatidyltransferase (CDIPT), and solute carrier family 16 member 1 (SLC16A1)
TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD
About this article Cite this article Alom, S., Ali, F., Nongkhlaw, F.T
Fer-1 faces bioavailability and metabolic stability obstacles, with a notably short plasma half-life and imperfect penetration through the BBB, limiting its use in neurodegenerative conditions [99, 228, 229]
For superoxide anion, the main ROS, a first line of defense is represented by the enzyme superoxide dismutase, localized in the mitochondrial matrix
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