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A mechanism for NRF2 induction is via an electrophilic quinone [161], because they act as cofactors for electron transport in cellular respiration and, due to their semiquinone radicals, are capable of redox cycling and forming ROS [162]

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In the superficial spinal dorsal horn and over short time periods NO is likely to be produced essentially by NOS localized in dorsal root ganglia and primary afferent terminals

doi: 10.1186/1479-5876-12-20 400 FeganKGBehanPOBellEJ

While I CO values close to zero have been reported for unaged PVC 56 , pristine PVC used in this study has a higher I CO because of the high content of C=O-containing DEHP 42