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The results were significant: Average weight loss of 20.7% of starting body weight over a span of 72 weeks among participants who stayed on treatment, compared to 17.5% with the standard 2.4 mg dose

Indian J Pediatrics

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This process was fundamental in order to buffer ROS flux and a consequent detrimental over increase of self-digestion ( Figure 2 )

For deeper or long-standing pigmentation, it can take 6 to 8 weeks