Nat Rev Neurol 21 , 687705 (2025)
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Nucleic Acids 33 , 559571 (2023)
G6PD deficiency can neither be prevented nor provoked
In KMT2A-rearranged AML, integrative multi-omics analyses identified a six-gene lactylation-associated signature (PFN1, S100A6, CBR1, LDHB, LGALS1, and PRDX1) that distinguishes this high-risk subtype from cytogenetically normal AML and associates with immune infiltration and metabolic pathway activity, defining molecular subtypes with distinct immunometabolism dependencies and suggesting potential sensitivity to PI3K, MEK, and proteasome inhibitors in signature-high cases [194]
In BT474, telomere length reached a maximum of 8 kb at a dose of 0.2 g /ml