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doi:10.34172/bi.30071

The F-box protein fbp1 shapes the immunogenic potential of cryptococcus neoformans

Prices NAD stands for nicotinamide adenine dinucleotide

Results vary between individuals

, NLR family pyrin domain containing 3 (NLRP3)) that sense pathogen-associated molecular patterns (PAMPs) or damage-associated molecular patterns (DAMPs), such as the accumulation of ROS or the efflux of potassium ions (K + )

In contrast to LPS stimulation, known to increase intracellular ROS and thus increase the intracellular GSH/GSSG ratio without changing total glutathione levels ( Supplementary Figure 3 ) (37), BDG exposure increases both the GSH/GSSG ratio and the total amount of intracellular GSH ( Figure 4D )