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Pallardo et al., 2009)

Final mechanistic insights Peptide mechanisms operate through precise molecular interactions, not magic or wishful thinking

Pharmacological management, on the other hand, not only centers on the use of neural-modulating agents, but also with agents to remodel the epigenetic chromatin landscape

In contrast, they have drawbacks, including poor membrane permeability, suboptimal therapeutic activity, and structural instability 48

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However, long-term fasting is typically not the primary cause of NAFLD, and results from such models should consequently be translated with caution