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The transferrin ligand itself, along with engineered peptides such as the T7 peptide (HAIYPRH), has demonstrated strong affinity for TfR

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Under normal conditions, iron in circulation is safely bound to the transport protein Tf, and intracellular iron is largely sequestered within the storage protein ferritin [95]

It has also been reported in several studies that GA has antianxiety (Meftahi and Aboutaleb 2023