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Thirty-four of the 51 patients reported a favorable response to the treatment, and 17 did not
For example, raloxifene, a selective estrogen receptor modulator used in therapy of osteoporosis, naturally has a low bioavailability and has also been shown to be extensively metabolised by UGT1A8 and UGT1A10 (Kemp et al., 2002)
It also reduces hepatic fat accumulation, which independently worsens insulin sensitivity a relevant secondary benefit given that non-alcoholic fatty liver disease is significantly more prevalent in women with PCOS
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