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In type 1 diabetes, mitochondrial ROS production during immune attack amplifies apoptotic signaling, while in type 2 diabetes, chronic metabolic stressors such as hyperglycemia and hyperlipidemia also increase ROS and damage mitochondria in insulin-sensitive tissues

These structural improvements translate to stronger, more fracture-resistant bone

Acknowledgments The authors acknowledge Ms

Melatonin is often referred to as the body's "sleep hormone," though it is more accurately described as a circadian signaling molecule that helps synchronize the sleep-wake cycle with environmental light and darkness and promotes sleep onset partly by lowering core body temperature

Chembiochem 2007, 8 (18), 21912194

& Timsit, E