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Step 3: Glutathione assembly Finally, the building blocks come together: Cysteine + glycine + glutamate = glutathione

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By using 1,1-dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodide (DiR), a near IR fluorescent and hydrophobic carbocyanine, as a fluorescence tracking agent, whole body imaging demonstrated that COXP micelles delivered DiR to mouse brains about 20 times higher than DiR administered alone [52]