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Fatigue while on tirzepatide may not be solely due to the medication itself

Rotate injection sites systematically to help prevent irritation and reduce the risk of lipohypertrophy

You might have gotten the shot on a weekend or right before attending a friends birthday or wedding

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Distinguishing direct pharmacological anti-inflammatory actions from secondary metabolic improvements requires further mechanistic studies and randomized controlled trials specifically designed to assess inflammatory outcomes as primary endpoints

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