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Within cells, cysteine participates in cell metabolism, whereas upon cell exit, cysteine is oxidized into cystine and rejoins the circulatory system

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FLS are predominant cells of the synovium and contribute to inflammatory and metabolic changes during joint diseases 22,35

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Hyperhomocysteinemia-Mediated Homocysteinylation Inconsistent with the hypothesis of an increased oxidant stress, a decrease in LDL susceptibility to oxidation and in plasma peroxidation indicators was reported in homozygous patients for CBS deficiency (Blom et al, 1992, 1995