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Although all unimolecular triple agonists in phase 2 trials for obesity are GLP1/GIP/GCG triple agonists, there is an ongoing phase 2 clinical trial of bioglutide, an oral insulin-like-growth factor-1 (IGF-1)/GLP-1/GIP/GCG quadruple agonist (NCT06564753) for individuals with obesity, which is also being trialled in combination with tirzepatide (NCT06643728)

Studies suggest that supplemental selenium could alleviate the toxic effect of excessive iodine intake on the thyroid

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As shown in Figure 1A, TPA treatment induced cutaneous hyper-proliferation in the basal diet group, whereas Protandim diet reduced the levels of hyperplasia