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All data were analyzed with SPSS statistical analysis software (version 22.0

There is evidence that women, especially after menopause, are more susceptible to the effects of tobacco smoke and develop a different pattern of disease with more severe small airway obstruction and less emphysema [23,24,25,26,27]

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4) To test for differences in daily carbonyls exposure derived by liquid consumption, carbonyl exposure per gram of aerosol yield was calculated and Friedman tests performed