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Importantly, nausea associated with semaglutide is typically mild to moderate in severity and transient in nature

- (PGC)

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How This Works Tirzepatide is a dual GLP-1/GIP receptor agonist : it activates both the GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) incretin receptors, which together regulate appetite, glucose-dependent insulin release and glucagon [1] [5]

Even though some therapeutic options are in place, they fail to work effectively in the presence of diabetes as there are metabolic and molecular abnormalities that compromise their efficacy in diabetic conditions