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Altogether, these results are consistent with CDK11 acting as a primary kinase for SF3B1 phosphorylation 8 , and suggest that P-SF3B1 is required for the efficient integration of SNIP1 and the RES complex to the spliceosome during its activation

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Journal of the American Chemical Society

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The effects of MVs on the transcription of ECM proteins Qualitative PCR results showed that hiPSCs-derived MVs treatment significantly increased collagen I1 and collagen III mRNAs expression in fibroblasts on days 3 and 5 of culture (Fig