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Together, these findings uncover the phosphorylation-dependent CDK11/P-SF3B1/SNIP1 signaling axis that is critical for pre-mRNA splicing and cellular proliferation and provide a mechanistic insight into its dysregulation in disease

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3) Ammonium reduces miR-27b-3p expression, enhancing apoptosis-related gene expression (e.g., TRADD, FADD), thus promoting both death receptor and mitochondrial pathway activation (112, 149)

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