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For intramuscular injections, 22-25 gauge is preferred, while for subcutaneous injections, 25-27 gauge is suitable

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Also, advise of any health or medication changes

The most common B12 subcutaneous injection sites are the following: The upper arm To self-administer a B12 injection into the arm, pinch a thick skin layer of the side or back of the upper arm and insert the needle at a right angle