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DIETARY REGULATORS OF GSTP1 EXPRESSION Since progressive GSTP1 hypermethylation is a hallmark biomarker but potentially also a driver of prostate cancer progression, various research teams were looking for dietary intervention to lower the methylation burden of GSTP1 gene promoter

Thiyl radicals (sulfur-centred) can transform to carbon-centred radicals via hydrogen atom exchange equilibria

One modulates an enzyme, the other activates a receptor

Risk factors include exceeding recommended doses (often unintentionally due to acetaminophen being in many combination products), chronic heavy alcohol use, poor nutrition, and existing liver disease