1c,d) and was previously suggested as a candidate for a potential activator site, first, because its positive charge might stabilize or bind GSH as GS , and, second, because of its evolutionary conserved position that is equivalent to the GSH-interacting catalytic residue of glutathione transferases 3
This work was supported by the Xinglin Scholar Disciplinary Talent Research Promotion Program of Chengdu University of Traditional Chinese Medicine, the Seedling Talent Special Project (MPRC2023035), the Natural Science Foundation of Sichuan Province (2023NSFSC1801), and the Special Research Project on Traditional Chinese Medicine of the Administration of Traditional Chinese Medicine of Sichuan Province (2024MS041)
According to many ancient medical books in China, Scorpio has a medicinal history of more than 1,000 years (Zhang et al., 2024)
& Ring, D
Targeting glutamine transporters and downstream enzymes involved in glutamine metabolism holds significant promise in enhancing anti-tumor immunity
Beneficial pleiotropic actions of melatonin in an experimental model of septic shock in mice: regulation of pro-/anti-inflammatory cytokine network, protection against oxidative damage and anti-apoptotic effects