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Over time, it has evolved to match shifting markets, regulations, and design trends, yet it has always maintained its distinctive character

Starting with balanced coffees and realistic expectations makes the transition easier

As a result, in 1966 the FTC discontinued its 1960 ruling which had banned tobacco companies from reporting tar and nicotine claims in advertising

Juul had submitted applications for only menthol- and tobacco-flavored products

We estimate that the amount of backfill funding needed to comply with this requirement would be at least $50 million but not more than $150 million annually, as shown in Figure 2

Additionally, the choice of flavor may change over the course of a smokers substitution of combustible tobacco with e-cigarettes, such that tobacco flavors are more popular when users start using e-cigarettes (Farsalinos et al., 2013)