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Intranasal delivery of mitochondria for treatment of Parkinsons Disease model rats lesioned with 6-hydroxydopamine

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Specific population Pediatric poisoning Pediatric patients may be at decreased risk of hepatotoxicity and severe APAP poisoning compared to adults based on the predominant sulfation pathway in patients

doi: 10.1038/s41598-021-81628-3 187 ZengX.TangS.DongX.DongM.ShaoR.LiuR.et al

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At concentration ranges typical to published preclinical protocols, the copper mass delivered by GHK-Cu is orders of magnitude below established acute toxicity thresholds