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Withanolides have anti-inflammatory and immunomodulating effects similar to glucocorticoid drugs, and act as anti-inflammatory agents by inhibiting lymphocyte proliferation, complement system, and delayed-type hypersensitivity

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It works by inhibiting an enzyme called tyrosinase, which is responsible for creating pigment

Half of those in the intervention group reported no moderate-to-severe hot flashes at week 12 while the control group remained unchanged