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Minnelide, a plant-derived compound, showed ability to deactivate CAFs and anti-tumour efficacy in preclinical models for pancreatic and liver cancers [450, 451]

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The glutathione peroxidase activity in the samples was measured using an absorbance spectrometer at 340 nm using a Glutathione Peroxidase Assay Kit (Cayman Chemicals, Ann Arbor, MI,703102)

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