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Assessment of voxel-wise T1 relaxation times in the NP ( n = 146,387 voxels) demonstrated that T1 values were more heterogeneous during the early stages of disc degeneration (Pfirrmann grades I and II) compared with later stages of degeneration (Pfirrmann grades IIIV

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Here, approximate levels of proteins were determined using the abundance of identified peptides without labeling such as 18 O or iTRAQ

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In particular, compared with granulosa cells in the control group (COGC), the expression of ferritinophagy-related genes that regulate ferroptosis was also abnormal in the EMGC group (Fig

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By integrating single-cell sequencing, synthetic biology, and AI screening technologies, we aim to establish an integrated platform for PDEVs that combines active component mapping-target prediction-precision delivery (Zeng et al., 2024), and provide green and efficient therapeutic solutions for reproductive disorders such as premature ovarian failure, recurrent implantation failures, and spermatogenic dysfunction (Shao et al., 2023

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