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Curcumin shows neuroprotective effects by stabilizing mitochondrial membrane potential, inhibiting cytochrome c release and subsequent caspase-3 activation, leading to reduced apoptosis (Kim et al., 2011)

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In the present report, we used a GST fusion version of the 8-kDa protein serine protease inhibitor Kazal-type 3 (SPINK3) as the bait to purify anti-SPINK3 antibodies from a rabbit crude serum

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Caspase-3/7 activity was directly assessed by CellEvent Caspase-3/7 Green Flow Cytometry Assay Kit in order to further evaluate the effect of GSB-106 and BDNF on downstream apoptotic pathway