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In addition, the extracellular ligand-binding domain of LRP2 binds to various large macromolecules, including lipoprotein lipase, apolipoproteins E and B, and albumin

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The inhibition profile of methylene blue on nitrovasodilator induced cyclic guanosine monophosphate accumulation was quantitatively reproduced by extracellular generation of superoxide anion with xanthine (100 uM) and xanthine oxidase (5 mU)