Resolution of fatty liver disease Even more striking than relative reduction was the rate of normalization
Science 343 , 1242782 (2014)
Wilson diseaseCurrently used anticopper therapy
majority of TBI and stroke studies Mice Used for transgenic Alzheimers models (APP, APP/PS1) and excitotoxicity studies Humans Multiple clinical trials in stroke, dementia, and TBI populations Cell culture Cortical neurons, hippocampal cultures, endothelial cells for mechanistic studies Research Limitations & Regulatory Status Critical Gaps in Current Evidence Despite over 1,000 preclinical studies and numerous clinical trials, Cerebrolysin faces substantial translational challenges that significantly limit its therapeutic utility
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[73 74 75] However, we did not receive data on improvements in access or outcomes for this patient population with the use of this technology
