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There are many reasons to try and optimize growth hormone and IGF-1 levels as we age, including helping to sustain lean muscle mass while preventing belly fat, maintaining healthy bone mineral density, and supporting heart and brain health

Practical Research Considerations A few practical points come up repeatedly in the research literature and community discussion: Weekly cadence

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Moreover, NO production in skeletal muscle is a direct consequence of contractile activity and influences several metabolic myocyte pathways under both physiological and pathological conditions