The oxidation of nicotinamide adenine dinucleotide phosphate was determined spectrophotometrically at 340 nm at 37C
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NPJ Vaccines 10, 24
The immune-damaging effects that PFAO caused in zebrafish kidneys showed that it changed the activity of NF-B transcription factors, which, in turn, changed the transcription of cytokines
Additionally, multi-cohort transcriptome analysis revealed that low tumor tissue MMP-9 mRNA expression was not only associated with longer OS (P=0.0012) and PFS (P=0.0066), but also significantly predicted the degree of survival benefit that patients received from standard TMZ chemoradiotherapy, whereas the high MMP-9 group had limited benefit, suggesting that tissue MMP-9 expression is a potential predictive biomarker of TMZ efficacy (65)