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HIF-1 downregulation increases ACSL4 to promote ferroptosis, and Nrf2 mediates HIF-1 activation to alleviate ischemic AKI (102)

Interestingly, iron deficiency also aggravated RM-induced AKI by enhancing catalytic heme-iron-modulated lipid peroxidation and DNA oxidation, upregulating the activity of p53/p21 and promoting cellular senescence [162]

Impact of fecal microbiota transplantation in severe alcoholic hepatitis: A systematic review and meta-analysis

Block, MD