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Furthermore, there were no significant negative impacts on liver function, renal function, hematology, or vital signsduring or after the supplementation period Supplementary Tables 24

The early detection and treatment of B12 deficiency are important because if left untreated, the neurological complications can become permanent

No unusual symptoms

Status Scheduled requires update after meeting Evidence update log 17 July 2026 Initial evidence review published using regulator, anti-doping, trial-registry and peer-reviewed sources

In animal and emerging human data, it upregulates VEGF (vascular endothelial growth factor) and FGF (fibroblast growth factor) to spark angiogenesis the creation of new blood vessels critical for healing

long-term human effects unknown