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It implies that the original docking conformation of CME_b may not be a reliable binding mode

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

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While the venom can cause immediate pain and swelling upon a sting, it also has the potential to exert beneficial effects, such as reducing inflammation and providing pain relief, when used in controlled therapeutic settings (Sadek, 2023)

For example, this might include chronic psychological pressure, poor sleep, blood sugar instability, subclinical infections, and environmental exposures such as mold and heavy metals