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Abnormalities in the PPP are primarily manifested as oxidative stress-induced compensatory activation

They are absorved by the human bowels and must also actuate like antioxidants

Most current evidence is pre-clinical

Along with other natural antioxidants, including vitamin C , beta-carotene and vitamin E , these important pigments guard the body from damaging effects of free radicals, which are unstable molecules that can destroy cells and play a role in many diseases

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Although administration of glutathione may have been associated with a rash in one patient in the current study, the causal associations between glutathione and other adverse effects are unclear