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The deficiency of selenium can be concomitant with that of vitamin E, another molecule with an antioxidant action

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Paired helical filaments and straight filaments contribute to the formation of NFTs, a hallmark of neurodegenerative disease ( Therapeutic approaches for tauopathies have multidimensional aspects, including targeting the post-translational modifications, tau aggregation, and tau clearance through the autophagy process with the help of lysosomes