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Data availability Transcriptomic and single-cell RNA-sequencing datasets generated in this study are publicly available

2 prefer K29 over K48

Additionally, MS1 spectra within a retention time range of 45 s or within a precursor m / z tolerance of 1.4 m / z were merged

Longer-Lasting Effects: The LR3 variant has a longer half-life compared to regular IGF-1, meaning its anabolic effects last longer in the body, leading to more significant results over time.

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Considering the evidence as a whole, natural phenolics and structurally atypical products regulate osteogenesis and angiogenesis through diverse signaling cascades and multi-cellular interactions