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, VelezdelValle, C

The pathophysiological mechanisms linking this persistence to post-COVID IBS likely involve: Sustained inflammatory responses with elevated interferon levels Expansion of activated immune cells even 8 months post-infection Intestinal dysbiosis affecting the gut-brain axis Increased intestinal permeability during and after infection These findings suggest that long-term GI symptoms after COVID-19 may stem from ongoing intestinal inflammation driven by viral persistence, rather than merely representing psychological sequelae of the acute illness

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Topical antibiotics like metronidazole and erythromycin are the primary prescription treatments, working through anti-inflammatory rather than antibacterial mechanisms

Vitamin B12, also known as cobalamin, is a water-soluble vitamin essential for various bodily functions