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Some evidence even suggests that e-cigarette use can actually impede smoking-cessation efforts

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10.22427/NTP-ICCVAM-ROADMAP2018 31 JATC (2020)

p53 can also negatively regulate other cellular pathways involved in glycolysis, such as the PI3K/AKT signalling pathway to suppress glycolysis in cells [67,68,69]

Department of Health and Human services, smoking-related illnesses cost the United States $300 billion each year