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This aesthetic argument is sometimes framed in terms of intrinsic beauty, where classical architecture is seen as objectively preferable, while in other instances it is based on empirical claims about public preferences for classical styles

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The K-means clustering algorithm divided 4126 DEPs (differentially expressed proteins) of the whole groups into 6 clusters, which was consistent with heatmap results

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These findings are supported by mechanistic investigations that have identified multiple pathways through which environmental toxicants can induce DNA fragmentation in spermatozoa, including oxidative stress, mitochondrial dysfunction, and direct genotoxic effects (67)