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doi: 10.1056/NEJMoa073493 16 International Multiple Sclerosis GeneticsCWellcome Trust Case ControlCSawcerSHellenthalGPirinenMSpencerCCet al

Regulation of glucose transporter protein-1 and vascular endothelial growth factor by hypoxia inducible factor 1 under hypoxic conditions in hep-2 human cells

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PMID: 26279367

Staphylococcus aureus , one of the earliest and most persistent pathogens found in the lungs of people with CF, has been shown to adapt to the lung environment by increasing pro-inflammatory cytokine secretion (e.g., TNF- or IL-8, involved in the mucin secretion pathway) through upregulating staphylococcal protein A (Spa) (Ramond et al., 2022)