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Eligible studies investigated the effects of tobacco exposure on microbial composition and its association with local or systemic pathophysiological outcomes, including inflammatory, metabolic, and neoplastic processes

The myriad flavours are also a major attraction

Mouth and throat: Cancer of the mouth and throat is common among smokers

But the days of puffing your way through a primetime ad break were over

For someone with a history of addiction or strong temptations to excess, yes, it could render even a single smoke a sin against prudence, given his personal history or makeup or both