Neurotensin and CRH interactions augment human mast cell activation
reported that a low molecular weight compound, 32-134D, effectively inhibits both HIF-1 and HIF-2 in an in vitro hepatocellular carcinoma model
The intramuscular administration of the human HGF gene reduced the rate of mortality, restrained inflammation and infiltration, and reduced renal fibrosis (Liu and Yang, 2006)
Enzyme/ROS dual-sensitive nanoplatform with on-demand Celastrol release capacity for enhanced ulcerative colitis therapy by ROS scavenging, microbiota rebalancing, inflammation alleviating
Older adults absorb less B12
While Phase II trials in heart failure and primary mitochondrial myopathy did not meet primary efficacy endpoints, the TAZPOWER trial in Barth syndrome demonstrated significant improvements in muscle strength and sixminute walk distance, leading to FDA accelerated approval in 2025 [3][10]