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Ostadmohammadi V, Jamilian M, Bahmani F, Asemi Z

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This suppression of the NF-B pathway contributes to the downregulation of pro-inflammatory mediators, thereby enhancing its therapeutic efficacy in psoriasis management

Its powerful antioxidant properties are known to improve skin clarity, reduce pigmentation, and even out skin tone

These findings collectively underscore the need to consider paternal health in preconception counseling and public health strategies

Initially described as a pro-atherogenic molecule due to its proliferative role in VSMC, it was further demonstrated that the effect of IGF-I on VSMC was to compensate for local apoptosis, and that, overall, IGF-I is not pro-atherogenic in native arteries but anti-atherogenic[320], mainly through enhanced nitric oxide production[308]