Made of three amino acids (cysteine, glycine, and glutamine), glutathione functions as a powerful antioxidant
copper complexation is typically performed by mixing the tripeptide with copper(II) salts (chloride, acetate, or sulfate) at controlled pH, with the resulting complex purified by chromatography
The 150,000-GSF facility is designed to maximize flexibility, as 20,000 GSF of open research laboratories flank 20,000 GSF of central laboratory core, including common equipment rooms, specialty labs, micropsy, tissue culture, imaging and glasswash divided by a central service corridor on the two upper floors
Cell Mol Life Sci 2005
Promising results have been demonstrated in the treatment of PD (Prabhakaran et al., 2023)
Loss of SLC25A39 reduces mitochondrial GSH import and abundance without affecting cellular GSH levels