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HDL from ischemic cardiomyopathy and CAD subjects also have reduced cholesterol efflux acceptance capacity, which likely leads to increased foam cell formation in the atherosclerotic lesion and increased atherogenesis (746,863)

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Antioxidant Response Elements: Discovery, Classes, Regulation and Potential Applications

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Dicarbonyls and advanced glycation end-products in the development of diabetic complications and targets for intervention

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Our study establishes that RSL3 contributes both to thyroid tumor cell DNA damage and concomitant inhibition of DNA damage repair response by limiting the availability of pNPM1 (T199)

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in tandem with other human factors such as the human leukocyte antigen (HLA), epigenetics, preexisting comorbidities (i.e., T2DM, CVD, obesity), age, preceding systemic impairments (i.e., hyperinflammation, micro-thrombosis, fibrosis, dysbiosis, autoimmunity, etc.), and socio-demographic factors (i.e., food security, environment, access to medical care) 22,27,28

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