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A1298C Variant (rs1801131): While this variant has a smaller impact on homocysteine levels, it has been associated with neurotransmitter imbalances, mood disorders, and chronic fatigue [5]

After proteolysis cleavage, the newly formed C-terminus of c-MET -chain inserts into a small pocket in HGF I-K1, which is mainly stabilized by the electrostatic interaction between Glu302 of c-MET and Arg197 of HGF (Fig

Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism

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Refsum et al., 1998)

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