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June 28 : The FDA declined to approve Eton Pharmaceuticalsdehydrated alcohol injection for the treatment of methanol poisoning, citing concerns related primarily to Chemistry Manufacturing and Controls. This is the second Complete Response Letter issued to Eton for this proposed treatment
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10.1111/1541-4337.70158 REFERENCES Abbasi, A
In addition, transcriptomic analysis of brains of 2 independent SCA3 transgenic mouse models reported downregulation of genes involved in glutamatergic and alpha-adrenergic neurotransmission and alterations in CREB pathways, as well as in axon guidance molecules, some of these alterations being already present at presymptomatic ages [117, 122]
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