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Because EWcp/UCN1/CART neurons express estrogen receptor beta and estrus cycle-related hormonal fluctuations modulate UCN1 levels, we recruited exclusively male mice in our study 85,86

However, overdose remains a leading cause of acute liver failure, primarily characterized by centrilobular (zone 3) hepatic necrosis, oxidative stress, mitochondrial dysfunction, and sterile inflammation

At a mechanistic level, DON-induced dysbiosis appears to intensify LPS-driven hepatic inflammation, as increased endotoxin translocation can activate inflammatory signaling cascades in the liver, leading to enhanced ROS production and lipid peroxidation (Rizzatti et al

To understand these complex relations and the vulnerable part of society, participation in the management system should be increased and the area of negotiation and dialogue should be kept wide

Glutathione is present in all cells but is especially concentrated in the liver