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It increased survival of cultured enteric neurons and proliferation of enteric glial cells, suggesting direct neuroprotective effects on the enteric nervous system that could influence central serotonin tone through vagal signaling

This hyper-proliferative state drains the body's metabolic energy and drives the profound fatigue seen in these conditions

What Is Prolotherapy

Gastrointestinal research represents one of the most extensively documented application areas

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In a recent study, Liskiewicz and colleagues discovered that long-acting GIP receptor agonists activate GABAergic neurons that express the GIP receptor in the area postrema, and that GIP receptor signaling in GABAergic neurons is necessary for the effects of GIP to lower body weight [151]