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PMID 14554208

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J Neurosci 43: 68166829, 2023

Inhibiting ferroptosis via iron chelators, radical-trapping agents, and other interventions demonstrates significant improvements in neuronal survival and synaptic function across diverse preclinical models, establishing ferroptosis targeting as a promising novel therapeutic strategy for AD

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By combining with serine, homocysteine is converted to cystathionine and then to further transmethylation products, namely cysteine, glutathione, taurine and finally sulfate all valuable components of antioxidant adaptation and detoxification